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Bioinformatics core

 

 
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Genomics Analysis

 Service Items: 

1.   SNP analysis and profiling

2.   Genome-wide association study (GWAS)

3.   De-novo genome annotation

4.   Epigenetics 

analysis

5.   Metagenomics 

analysis

6.   Pharmacogenomics analysis
 

 

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Transcriptomics Analysis

 Service Items:

1.   mRNA/small RNA/micro RNA differential expression

2.   mRNA alternative splicing

3.   De-novo RNA sequencing analysis

4.   Gene set enrichment analysis (GSEA)

 
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Proteomics Analysis

 Service Items: 

1.   Protein structure and post-translational modification

2.   De-novo protein sequencing analysis

3.   Protein-DNA/RNA/protein interaction
 

 
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Systems Biology Analysis

 Service Items:

1.   Pathway reconstruction (from experimental data)

2.   Pathway network analysis

3.   Pathway perturbation analysis (under SNPs/drugs/ environmental factors)

 

Advisory Committee

Li, Yu-Chuan
Professor, Graduate Institute of Biomedical Informatics

Hsu, Chien-Yeh
Professor, Graduate Institute of Biomedical Informatics

Liu, Chien-Tsai
Professor, Graduate Institute of Biomedical Informatics

 

Service Faculty Team

Lee, Yuan-Chii
Associate Professor, Graduate Institute of Biomedical Informatics

Research Fields: Cancer genomics, Research of cancer metastatic mechanisms, Neuro disease genomics

Expertise:

-    Microarray data analysis

-    Next Generation Sequencing data analysis

-    Gene enrichment functional annotation

 

Chang, Wei-Chiao
Associate Professor, Master Program for Clinical Pharmacogenomics and Pharmacoproteomics

Research Fields: Pharmacogenomics, Disease-gene association study, Single-cell calcium ion image analysis

Expertise:

-    Discovery for rare variants, SNP, somatic mutations (by exome sequencing)

-    Functional analysis for disease/drug and genomics association

-    Detection of real-time single cell calcium mobilization

 

Wang, Wen-Chang
Assistant Professor, Ph.D. Program for Translational Medicine

Research Fields: Genetic epidemiology, Genetic statistics

Expertise:

-    Genetic linkage analysis

-    Genetic association analysis

-    High-throughput genomic data analysis

-    False discovery rate (FDR) analysis

-    Biostatistics

 

Chang, Yo-Cheng (core manager)
Assistant Professor, Graduate Institute of Biomedical Informatics

Research Fields: Systems biology, Pathway analysis, Genome sequencing and annotation, Integrative omics data analysis

Expertise:

-    Mining potential biomarkers and drug targets through systems biology approach

-    Next-generation sequencing and microarray data analysis

-    Signaling / Regulatory / Metabolic pathway reconstruction and network analysis

-    Pathway perturbation analysis under SNPs / drugs / environmental factors

 

Chang, Tzu-Hao (core manager)
Assistant Professor, Graduate Institute of Biomedical Informatics

Research Fields: Regulatory RNAs, Protein post-translational modifications, Epigenetics, Metagenomics

Expertise:

-    Integrative analysis for microarray and next-generation sequencing data in various biological applications

-    Cooperation in Interdisciplinary biological research

-    Identification of novel biomarkers for diagnosis and prognosis

-    Development of biological tools and databases

 

Huang, Tsui-Chin
Assistant Professor, Ph.D. Program for Cancer Biology and Drug Discovery

Research Fields: Exploring cancer progression and anti-cancer drug mechanisms using systems biology approach

Expertise:

-    Systems biology

-    Proteomics

-    Cancer biology

-    Signaling pathway analysis

 

Su, Chia-Yu
Assistant Professor, Graduate Institute of Biomedical Informatics

Research Fields: Computational biology, Proteomics, Protein structure and function prediction analysis, Data mining

Expertise:

-    Computational biology

-    Proteomics

-    Protein structure and function prediction analysis

-    Data mining

 

Contact

Please email to core managerbioinfo@tmu.edu.tw. We will reply as soon as possible.